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doi: 10.2131/jts.33.599 29 ShenY

D.ShelerudR

304 The cell-type-specific role of COX-2 has also been validated in a diabetic nephropathy model: macrophage and podocyte COX-2 signaling activation and PGE2 release significantly lessen the severity of diabetic kidney disease, unlike the pathogenic effects of COX-2 in intrinsic renal cells